Summary: Potatoes consist of flavonoids that provide health benefits for human consumers.To learn more about how potato tuber flavonoid accumulation and flesh pigmentation are 355 maybelline fit me controlled, we analyzed the transcriptomic and metabolomic profile of potato tubers from three colored potato clones at three developmental phases using
Chromatin regulation is critical for differentiation and disease.However, features linking the chromatin environment of stem cells with disease remain largely unknown.We explored chromatin accessibility in embryonic and multipotent stem cells and unexpectedly identified widespread chromatin accessibility at repetitive elements.Integrating genomic a
Abstract Background Electronic medical records contain information of value for research, but contain identifiable and often highly sensitive confidential information.Patient-identifiable information cannot in general be shared outside clinical care teams without explicit consent, but anonymisation/de-identification allows research uses of clinical
Cdc48/p97, a ubiquitin-selective chaperone, orchestrates the function of E3 ligases and deubiquitylases (DUBs).Here, we identify a new function of Cdc48 in ubiquitin-dependent regulation of mitochondrial dynamics.The DUBs Ubp12 and Ubp2 exert opposing effects on mitochondrial fusion and cleave different ubiquitin chains on the mitofusin Fzo1.We dem